Keywords
células fusiformes
tráquea
sarcomatoide Squamous cell carcinoma
spindle cells
trachea
sarcomatoid
How to Cite
Abstract
Spindle cell squamous carcinoma (SCSC) of the trachea is a rare malignant neoplasm, histologically characterized by the presence of spindle-shaped cells arranged in solid, storiform, or fascicular patterns. Clinically, it typically presents with nonspecific respiratory symptoms, and its diagnosis poses a challenge due to its resemblance to sarcomas and other spindle cell lesions, making thorough histopathological and immunohistochemical evaluation necessary. The spindle cell component may express mesenchymal markers such as vimentin, SMA, cytokeratins, and p40. SCSC is believed to arise from the dedifferentiation of conventional squamous cell carcinoma. Surgical resection is the treatment of choice, complemented by radiotherapy in selected cases. We present the case of a 66-year-old patient with an obstructive tracheal lesion diagnosed as spindle cell squamous carcinoma.
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