Palabras clave
apocrino
ecrino
adenocarcinoma
enfermedad de Paget extramamario
escroto
GCDFP-15 Sweat gland
apocrine
eccrine
adenocarcinoma
extramammary Paget's disease
scrotum
GCDFP-15
Cómo citar
Resumen
El adenocarcinoma de glándula sudorípara es una neoplasia rara de histogénesis desconocida, su localización en escroto se ha documentado en escasos reportes de casos; se asocia frecuentemente a Enfermedad de Paget extramamaria. En este artículo reportamos un caso de un hombre de 66 años que debuta con lesión tipo placa eritematosa indurada en la piel del escroto acompañado de dolor, edema de extremidad inferior izquierda, con evidencia por estudios de imágenes de actividad tumoral en hígado y linfadenitis inguinal. En algunos reportes de casos se ha documentado que la expresión de Her2 y receptores de andrógenos es un indicador de mal pronóstico en estadios avanzados de la enfermedad.
Este caso destaca la agresividad potencial de estos tumores y la importancia de evaluar biomarcadores como HER2, que podrían orientar terapias dirigidas en un contexto con opciones limitadas. Se enfatiza la necesidad de un enfoque multidisciplinario para su manejo, dada su rareza y comportamiento clínico variable.
Citas
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