SOLID AND CYSTIC EOSINOPHILIC RENAL CELL CARCINOMA IN A PEDIATRIC PATIENT WITH TUBEROUS SCLEROSIS: CASE REPORT.
Vol. 4 No. 3 (2024), Artículos originales
Vol. 4 No. 3 (2024)

SOLID AND CYSTIC EOSINOPHILIC RENAL CELL CARCINOMA IN A PEDIATRIC PATIENT WITH TUBEROUS SCLEROSIS: CASE REPORT.

Artículos originales
https://doi.org/10.17811/ap.v4i3.22229
Published 2025-01-09
Alejandro Cardona Palacio
Departamento de Patología, Hospital Pablo Tobón Uribe y Universidad EIA, Medellín, Colombia
Susana Rivera Cardona
Universidad EIA, Envigado, Colombia
Alejandro Vélez Hoyos
Universidad EIA, Envigado, Colombia
Sigifredo Ospina Ospina
Profesor de la Universidad EIA, Medellín, Colombia
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Keywords

carcinoma de células renales sólido quístico y eosinofílico
esclerosis tuberosa
reporte de caso Eosinophilic solid and cystic renal cell carcinoma
tuberous sclerosis
case report

How to Cite

Cardona Palacio, A., Rivera Cardona, S., Vélez Hoyos, A., & Ospina Ospina, S. (2025). SOLID AND CYSTIC EOSINOPHILIC RENAL CELL CARCINOMA IN A PEDIATRIC PATIENT WITH TUBEROUS SCLEROSIS: CASE REPORT. Archives of Pathology, 4(3), 10–17. https://doi.org/10.17811/ap.v4i3.22229
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Abstract

Eosinophilic solid and cystic renal cell carcinoma is a rare subtype of clear cell renal cell carcinoma, described since 1976 and included in the latest edition of the WHO Classification of Urinary and Genital Tumors. This renal carcinoma shows a characteristic CK20 positive and CK7 negative immunohistochemistry, its incidence is unknown and it represents 0.2% of all clear cell renal carcinomas. Its presentation is usually indolent, but there are records of more aggressive presentations with metastatic disease. The case of a 7-year-old patient with a history of tuberous sclerosis and de novo complex kidney injury is reported.

https://doi.org/10.17811/ap.v4i3.22229
PDF (Español (España))

References

Tu Y, Feng R, Wang B, Hao J. Rare CT and MRI findings of eosinophilic solid and cystic renal-cell carcinoma. Asian J Surg. 2023 Jun 1;46(6):2650–1.

Mohanty SK, Lobo A, Cheng L. The 2022 revision of the World Health Organization classification of tumors of the urinary system and male genital organs: advances and challenges. Hum Pathol. 2023 Jun 1;136:123–43.

Goldblum JR, Lamps LW, Mckenney JK, Myers JL. Surgical Surgical. Rosai Acherman Surgical Pathology. 2018;703–23.

Taze D, Roulson JA. A case of a novel entity: eosinophilic solid and cystic renal cell carcinoma. Diagn Histopathol [Internet]. 2022 Jun 1 [cited 2023 Oct 30];28(6):309–11. Available from: http://www.diagnostichistopathology.co.uk/article/S1756231722000524/fulltext

Saremi N, Matsika A, Srinivasan B. Eosinophilic solid and cystic renal cell carcinoma with monosomy of chromosomes X and 3. Pathology [Internet]. 2020 Feb 1 [cited 2023 Oct 30];52:S86. Available from: http://www.pathologyjournal.rcpa.edu.au/article/S0031302520302889/fulltext

Argani P. A Molecular Marker for Eosinophilic Solid and Cystic Renal Cell Carcinoma. Eur Urol. 2018 Oct 1;74(4):487–8.

Zhou M. Eosinophilic solid cystic renal cell carcinoma. Uropathology, Second Edition. 2023 Jan 1;363–4.

MacLennan GT, Cheng L. Neoplasms of the Kidney. Urologic Surgical Pathology. 2020 Jan 1;83-163.e23.

Tretiakova MS. Eosinophilic solid and cystic renal cell carcinoma mimicking epithelioid angiomyolipoma: series of 4 primary tumors and 2 metastases. Hum Pathol. 2018 Oct 1;80:65–75.