Keywords
síndrome de Sézary
inmunohistoquímica
linfoma de células T Mycosis fungoides
Sézary syndrome
immunohistochemistry
T-cell lymphoma
How to Cite
Abstract
Cutaneous T-cell lymphomas represent a rare type of non-Hodgkin lymphoma. Mycosis fungoides and Sézary syndrome are the most common and representative variants of cutaneous T-cell lymphomas. Both neoplasms occur primarily in older adults, with a peak incidence between 50 and 70 years of age. This paper analyzes the case of a 49-year-old male patient who presented with a 7-month history of clinical symptoms characterized by unmeasured fever, pruritic erythroderma, and generalized lymphadenopathy. A skin and cervical lymphadenopathy biopsy was performed, revealing histopathological evidence of mycosis fungoides. Immunohistochemistry revealed atypical lymphocytes in the papillary dermis and epidermis expressing CD3 and CD4, while CD8 and CD20 were negative. Clinico-pathological evaluation led to a diagnosis of mycosis fungoides.
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